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Biomedical Research in Melanoma

Our group is dedicated to relevant clinical questions related to melanoma and other skin conditions. During this year we have continued to investigate what are the causes for melanoma development. In this regard, we have made important discoveries that explain, at least in part, how UV-irradiation cooperates with one of the main drivers of melanoma (BRAFV600E)?. In addition to this, we also have contributed to the description of novel genetic variants of proteins that mediate the immune response in melanoma that might have an impact in the antitumoral response. In a clinical setting, we have contributed to the development of algorithms to calculate the risk of getting melanoma in transplanted patients, the understanding of pathways involved in the cutaneous inflammatory diseases such as Lupus Erythematosus and the description of the viral dynamics of monkeypox infection in patients.

eCORE

  • Cancer

Team

Group Leader
Juan Angel Recio Conde, Vicente García-Patos Briones

Researchers
Kimberley MacGrail

PhD Students
Paula Granado Martínez, Roberto Orsenigo, Carlos González Cruz, Yuxin Ding, Berta Ferrer

Publications

11
Publications
63.6
%Q1
123.40
Impact Factor
11.22
Average Impact Factor

Solé C, Domingo S, Penzo E, Moliné T, Porres L, Aparicio G, Ferrer B, Cortés-Hernández J.
Downregulation of miR-885-5p Promotes NF-κB Pathway Activation and Immune Recruitment in Cutaneous Lupus Erythematosus.
J Invest Dermatol. 2023 Feb;143(2):209-219.e13.
DOI: 10.1016/j.jid.2022.08.036.
IF: 7.59

Gómez-Tomás Á, Bouwes Bavinck JN, Genders R, González-Cruz C, de Jong E, Arron S, García-Patos V, Ferrándiz-Pulido C
External Validation of the Skin and UV Neoplasia Transplant Risk Assessment Calculator (SUNTRAC) in a Large European Solid Organ Transplant Recipient Cohort.
JAMA Dermatol. 2023 Jan 1;159(1):29-36
DOI: 10.1001/jamadermatol.2022.4820
IF: 11.816

Suñer C, Ubals M, Tarín-Vicente EJ, Mendoza A, Alemany A, Hernández-Rodríguez Á, Casañ C, Descalzo V, Ouchi D, Marc A, Rivero À, Coll P, Oller X, Miguel Cabrera J, Vall-Mayans M, Dolores Folgueira M, Ángeles Melendez M, Agud-Dios M, Gil-Cruz E, Paris de Leon A, Ramírez Marinero A, Buhiichyk V, Galván-Casas C, Paredes R, Prat N, Sala Farre MR, Bonet-Simó JM, Farré M, Ortiz-Romero PL, Clotet B, García-Patos V, Casabona J, Guedj J, Cardona PJ, Blanco I; Movie Group; Marks M, Mitjà O.
Viral dynamics in patients with monkeypox infection: a prospective cohort study in Spain.
Lancet Infect Dis. Apr;23(4):445-453.
DOI: 10.1016/S1473-3099(22)00794-0.
IF: 71.421

Projects

Oncogene-mediated intratumoral immune-cell populations at different organs as biomarkers of immunotherapy response
Principal Investigator: Juan Angel Recio Conde
Agency: Instituto de Salud Carlos III FIS
Funding: 341,000 €
Period: 2021-2023

Molecular mechanisms in melanoma
Principal Investigator: Juan Angel Recio Conde
Agency: 2021 SGR00653 Generalitat de Catalunya
Funding: 60,000 €
Period: 2022-2025

VHIR Annual Report 2023