The Liver Diseases group is a referent in research in the liver diseases field at national and international level. We are national leaders in clinical trials covering all the spectrum of liver diseases. Another essential feature of the group is the active contribution of our members in the most significant national and international medical societies of the liver field (Executive and Scientific Committees of AEEH, Governing Board of EASL). Additionally, we have been collaborating in international consortiums and projects funded by European institutions such as EU-PEARL, LiverScreen, Decision, among others.
eCORE
- Advanced Therapies and Advanced Interventions, Nanomedicine, Transplant & Donation
- Chronic, Prevalent Diseases & Aging
Team
Group Leader
Joan Genescà Ferrer
Principal Investigator (PI)
Maria Buti Ferret, Isabel Campos Varela, Juan Ignacio Esteban Mur, Maria Martell Pérez-Alcalde, Beatriz Mínguez Rosique, Juan Manuel Pericàs Pulido, Josep Quer Sivila, Maria Del Mar Riveiro Barciela, Macarena Simon-Talero Horga, Victor Manuel Vargas Blasco, Meritxell Ventura Cots
Researchers
Lluis Castells Fusté, Immaculada Raurell Saborit, David Tabernero Caellas, Mònica Pons Delgado, Jordi Llaneras Artigues, Adriana Palom Agusti, Mónica Higuera Urbano
PhD Students
María Bermúdez Ramos, Meritxell Llorens Revull, Joan Martínez Campreciós, Elena Vargas Accarino, Judit Vidal Gonzalez, Ares Aurora Villagrasa Vilella, César Jiménez, Maria Luisa Roade Tato, Marta Ibañez Lligoña, Maria Martínez Gómez, Ana Barreira, Cristina Marcos, Sergi Colomer Castell, Carolina Campos Martinez, Juan Carlos Ruiz Cobo, Ana Feliu, Sergio Muñoz Martínez
Lab Technicians
Damir Garcia Cehic
Nursing and Technical Staff
Susana Anton Calvo, Cristina Adame Castillo, Elena de Sena Fernández, Ester Palacio Gutierrez, Marcella Salzano, Maria Margarita Torrens Buscató, Judit Vico Romero, Laura Puente Ramo, Clara Sabiote Cartes, Claudia Ana Burillo
Publications
Serra-Burriel M, Juanola A, Serra-Burriel F, Thiele M, Graupera I, Pose E, Pera G, Grgurevic I, Caballeria L, Piano S, van Kleef L, Reichert M, Roulot D, Pericas JM, Schattenberg JM, Tsochatztis EA, Guha IN, Garcia-Retortillo M, Hernandez R, Hoyo J, Fuentes M, Exposito C, Martinez A, Such P, Madir A, Detlefsen S, Tonon M, Martini A, Ma AT, Pich J, Bonfill E, Juan M, Soria A, Carol M, Gratacos-Gines J, Morillas RM, Toran P, Navarrete JM, Torrejon A, Fournier C, Llorca A, Arslanow A, de Koning HJ, Cucchietti F, Manns M, Newsome PN, Hernaez R, Allen A, Angeli P, de Knegt RJ, Karlsen TH, Galle P, Wong VW, Fabrellas N, Castera L, Krag A, Lammert F, Kamath PS, Gines P, Alvarez M, Andersen P, Angeli P, Ardevol A, Arslanow A, Beggiato L, Ben Abdesselam Z, Bennett L, Boutouria B, Brocca A, Broquetas MT, Caballeria L, Calvino V, Camacho J, Capdevila A, Carol M, Castera L, Cervera M, Cucchietti F, de Fuentes A, de Knegt R, de Koning HJ, Detlefsen S, Diaz A, Dieguez Bande J, Esnault V, Fabrellas N, Falco JL, Fernandez R, Fournier C, Fuentes M, Galle P, Garcia E, Garcia-Retortillo M, Garrido E, Gines P, LiverScreen Consortium Investigators.
Development, validation, and prognostic evaluation of a risk score for long-term liver-related outcomes in the general population: a multicohort study
Lancet. 2023 Aug 9:S0140-6736(23)01174-1
DOI: 10.1016/S0140-6736(23)01174-1
IF: 168.90
Pericas JM, Tacke F, Anstee QM, Di Prospero NA, Skalshoj Kjaer M, Mesenbrink P, Koenig F, Genesca J, Ratziu V, Di Prospero NA, Ratziu V, Pericas JM, Skalshoj Kjaer M, Anstee QM, Tacke F, Mesenbrinck P, Rivera-Esteban J, Koenig F, Sena E, Manzano R, Genesca J, Pais R, Kara L, Meyer E, Duca A, Kline T, Aaes-Jorgensen A, Balthaus T, de Preville N, Zhang L, Capuano G, Morello S, Mielke T, Hernandez Penna S, Posch M
Platform trials to overcome major shortcomings of traditional clinical trials in non-alcoholic steatohepatitis? Pros and Cons
J Hepatol. 2023 Feb;78(2):442-447
DOI: 10.1016/j.jhep.2022.09.021
IF: 25.7
Retat L, Webber L, Jepsen P, Martin A, Pinto HC, Lazarus JV, Negro F, Mitchyn M, Guzek J, Card-Gowers J, Graff H, Nahon P, Sheron N, Sagi SZ, Buti M
Preventing liver disease with policy measures to tackle alcohol consumption and obesity: the HEPAHEALTH II study
J Hepatol. 2023 Dec 2:S0168-8278(23)05297-2
DOI: 10.1016/j.jhep.2023.11.021
IF: 25.7
Riveiro-Barciela M, Barreira-Diaz A, Callejo-Perez A, Munoz-Couselo E, Diaz-Mejia N, Diaz-Gonzalez A, Londono MC, Salcedo MT, Buti M
Retreatment with Checkpoint inhibitors after a severe immune-related hepatitis: Results from a prospective multicenter study
Clin Gastroenterol Hepatol. 2023 Mar;21(3):732-740
DOI: 10.1016/j.cgh.2022.03.050
IF: 12.6
Pons M, Esteban JR, Ma MM, Davyduke T, Delamarre A, Hermabessiere P, Dupuy J, Lai-Hung Wong G, Cheuk-Fung Yip T, Pennisi G, Tulone A, Camma C, Petta S, de Ledinghen V, Wai-Sun Wong V, Augustin S, Pericas JM, Abraldes JG, Genesca J
Point-of-care non-invasive prediction of liver-related events in patients with NAFLD
Clin Gastroenterol Hepatol. 2023 Aug 11:S1542-3565(23)00626-2
DOI: 10.1016/j.cgh.2023.08.004
IF: 12.6
Projects
Caracterización de las claves fisiopatológicas y fenotipos de la enfermedad del hígado graso metabólica con ingesta moderada de alcohol para identificar nuevas terapias (ReLiveR).
Principal Investigator: Meritxell Ventura Cots / Juan Manuel Pericàs
Agency: Instituto de Salud Carlos III
Funding: 183,920 €
Period: 2023-2025
Aislamiento y caracterización molecular de Células Tumorales Circulantes (CTCs): potenciales biomarcadores en Carcinoma Hepatocelular
Principal Investigator: Beatriz Mínguez Rosique
Agency: Instituto de Salud Carlos III
Funding: 183,920 €
Period: 2022-2024
Impact of HLA haplotypes and HDV viremia in developing of clinical events and quality of life of patients with chronic hepatitis delta
Principal Investigator: Maria Buti Ferret / Mar Riveiro-Barciela
Agency: Instituto de Salud Carlos III
Funding: 117,370 €
Period: 2021-2025
EU Patient- cEntric clinicAl tRial pLatform – EU PEARL
Principal Investigator: Joan Genescà Ferrer
Agency: The Innovative Medicines Initiative
Funding: 1,987,375€
Period: 2019-2023
DECOMPENSATED CIRRHOSIS: IDENTIFICATION OF NEW COMBINATORIAL THERAPIES BASED ON SYSTEM APPROACHES- DECISION_H2020-SC1-BHC2019
Principal Investigator: Joan Genescà Ferrer
Agency: EUROPEAN COMMISSION
Funding: 130,472.5 €
Period: 2020-2025