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Stroke Research

In 2023, the Stroke Research Group was involved in several ongoing research projects. Notable among them are TRUSTroke, focused on trustworthy AI for improving stroke outcomes; HARMONICS, which aims to improve stroke care in Europe; VALIDATE, which validates an AI system to enhance stroke treatment; RACETOLL, a clinical trial evaluating a neuroprotective treatment in ambulances; RES-Q PLUS, developing solutions based on a global registry of stroke care quality. Additionally, they are fostering NoraHealth, a spin-off dedicated to individualized patient management and medical data visualization.

eCORE

  • Brain & Mind and Behaviour
  • Chronic, Prevalent Diseases & Aging
  • Global Health
  • Personalized Medicine, Innovative Diagnostics, Molecular Imaging & Digital Health

Team

Group Leader
Carlos Molina Cateriano

Principal Investigator (PI)
Estela Sanjuan, Marta Rubiera, David Rodríguez, Estefania Montiel, Jorge Pagola, Manuel Requena, Marc Ribó, Marta Olivé, María Ángeles Muchada

Researchers
Alejandro Tomasello, Jiahui Li, Noelia Rodríguez, Olalla Pancorbo

PhD Students
Federica Rizzo, Pere Canals, Marc Rodrigo

Nursing and Technical Staff
Claudia Meza, María Victoria Sala, Carole Conforti, Cristina Losada, David Cano, Ester Sánchez, Judith Cendrero, Lidia García, María Baladas, Cristina Guirao, Carolina Paredes, Riccardo Tiberi, Renato Simonetti, Maria Franco, Blanca Sastre, Jesús David González

Publications

79
Publications
60.8
%Q1
668.80
Impact Factor
8.44
Average Impact Factor

Sarraj A, Hassan AE, Abraham MG, Ortega-Gutierrez S, Kasner SE, Hussain MS, Chen M, Blackburn S, Sitton CW, Churilov L, Sundararajan S, Hu YC, Herial NA, Jabbour P, Gibson D, Wallace AN, Arenillas JF, Tsai JP, Budzik RF, Hicks WJ, Kozak O, Yan B, Cordato DJ, Manning NW, Parsons MW, Hanel RA, Aghaebrahim AN, Wu TY, Cardona-Portela P, Pérez de la Ossa N, Schaafsma JD, Blasco J, Sangha N, Warach S, Gandhi CD, Kleinig TJ, Sahlein D, Elijovich L, Tekle W, Samaniego EA, Maali L, Abdulrazzak MA, Psychogios MN, Shuaib A, Pujara DK, Shaker F, Johns H, Sharma G, Yogendrakumar V, Ng FC, Rahbar MH, Cai C, Lavori P, Hamilton S, Nguyen T, Fifi JT, Davis S, Wechsler L, Pereira VM, Lansberg MG, Hill MD, Grotta JC, Ribo M, Campbell BC, Albers GW; SELECT2 Investigators.
Trial of Endovascular Thrombectomy for Large Ischemic Strokes
N Engl J Med. 2023 Apr 6;388(14):1259-1271
DOI: 10.1056/NEJMoa2214403
IF: 158.5

Hernández-Jiménez M, Abad-Santos F, Cotgreave I, Gallego J, Jilma B, Flores A, Jovin TG, Vivancos J, Hernández-Pérez M, Molina CA, Montaner J, Casariego J, Dalsgaard M, Liebeskind DS, Cobo E, Castellanos M, Portela PC, Masjuán J, Moniche F, Tembl JI, Terceño Izaga M, Arenillas JF, Callejas P, Olivot JM, Calviere L, Henon H, Mazighi M, Piñeiro D, Pugliese M, González VM, Moro MA, Garcia-Tornel A, Lizasoain I, Ribo M
Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial
JAMA Neurol. 2023 Aug 1;80(8):779-788
DOI: 10.1001/jamaneurol.2023.1660
IF: 29

Ramos-Pachón A, Rodríguez-Luna D, Martí-Fàbregas J, Millán M, Bustamante A, Martínez-Sánchez M, Serena J, Terceño M, Vera-Cáceres C, Camps-Renom P, Prats-Sánchez L, Rodríguez-Villatoro N, Cardona-Portela P, Urra X, Solà S, Del Mar Escudero M, Salvat-Plana M, Ribó M, Abilleira S, Pérez de la Ossa N, Silva Y; RACECAT Trial Investigators.
Effect of Bypassing the Closest Stroke Center in Patients with Intracerebral Hemorrhage: A Secondary Analysis of the RACECAT Randomized Clinical Trial
JAMA Neurol. 2023 Oct 1;80(10):1028-1036
DOI: 10.1001/jamaneurol.2023.2754
IF: 29

Sarraj A, Kleinig TJ, Hassan AE, Portela PC, Ortega-Gutierrez S, Abraham MG, Manning NW, Siegler JE, Goyal N, Maali L, Blackburn S, Wu TY, Blasco J, Renú A, Sangha NS, Arenillas JF, McCullough-Hicks ME, Wallace A, Gibson D, Pujara DK, Shaker F, de Lera Alfonso M, Olivé-Gadea M, Farooqui M, Vivanco Suarez JS, Iezzi Z, Khalife J, Lechtenberg CG, Qadri SK, Moussa RB, Abdulrazzak MA, Almaghrabi TS, Mir O, Beharry J, Krishnaiah B, Miller M, Khalil N, Sharma GJ, Katsanos AH, Fadhil A, Duncan KR, Hu Y, Martin-Schild SB, Tsivgoulis GK, Cordato D, Furlan A, Churilov L, Mitchell PJ, Arthur AS, Parsons MW, Grotta JC, Sitton CW, Ribo M, Albers GW, Campbell BCV
Association of Endovascular Thrombectomy vs Medical Management With Functional and Safety Outcomes in Patients Treated Beyond 24 Hours of Last Known Well: The SELECT Late Study
JAMA Neurol. 2023 Feb 1;80(2):172-182
DOI: 10.1001/jamaneurol.2022.4714
IF: 29

Lavallée PC, Charles H, Albers GW, Caplan LR, Donnan GA, Ferro JM, Hennerici MG, Labreuche J, Molina C, Rothwell PM, Steg PG, Touboul PJ, Uchiyama S, Vicaut É, Wong LKS, Amarenco P; TIAregistry.org Investigators
Effect of atherosclerosis on 5-year risk of major vascular events in patients with transient ischaemic attack or minor ischaemic stroke: an international prospective cohort study
Lancet Neurol. 2023 Apr;22(4):320-329
DOI: 10.1016/S1474-4422(23)00067-4
IF: 48

Projects

HARMONICS. Harmonization and Implementation of High Value Stroke Care
Principal Investigator: Carlos Molina
Agency: European Commission
Funding: 468,090 €
Period: 01/01/2022 - 31/12/2024

VALIDATE: Validation of a Trustworthy AI-based Clinical Decision Support System for Improving Patient Outcome in Acute Stroke Treatment
Principal Investigator: Marta Rubiera
Agency: European Commission
Funding: 567,950€
Period: 01/05/2022 - 30/04/2026

TRUSTroke: TRUSTWORTHY AI FOR IMPROVEMENT OF STROKE OUTCOMES
Principal Investigator: Carlos Molina
Agency: European Commission
Funding: 760,000 €
Period: 01/05/2023 – 30/04/2027

Clinical trial to evaluate the administration of ApTOLL in ambulances and the neuroprotective effect in stroke patients. RACETOLL
Principal Investigator: Marc Ribó
Agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 437,334€
Period: 01/03/2022 - 28/02/2025

RES-Q PLUS: Comprehensive solutions of healthcare improvement based on the global Registry of Stroke Care Quality
Principal Investigator: Carlos Molina
Agency: European Commission
Funding: 396,730€
Period: 01/10/2022 - 30/09/2026

Patents

Nora Health
Priority Number: -
Priority Date: -
Applicants: VHIR

VHIR Annual Report 2023